Percepção positiva e eficácia das meias de compressão na prevenção de edema em membros inferiores de gestantes / Positive perception and efficacy of compression stockings for prevention of lower limb edema in pregnant women

Resumo Contexto A gravidez é caracterizada por mudanças fisiológicas que podem contribuir para o desenvolvimento de varizes, insuficiência venosa e edema das pernas. Objetivos Avaliar o efeito das meias de compressão em edema de membros inferiores e a percepção sobre o uso por gestantes. Métodos Trata-se de um ensaio clínico randomizado, controlado, prospectivo, paralelo e cego realizado com 60 mulheres grávidas distribuídas aleatoriamente em dois grupos: grupo intervenção (n = 30), que usou meias de compressão, e grupo controle (n = 30). Foram realizadas medições padronizadas de tornozelo e panturrilha, empregando-se fita métrica, em todos os 120 membros inferiores. No final do estudo, foi aplicado também um questionário para verificação das dificuldades e vantagens percebidas com relação ao uso das meias de compressão. Resultados As gestantes do grupo intervenção apresentaram aumento significativamente menor (p < 0,05) nos diâmetros de panturrilha e tornozelo em relação ao grupo controle. As diferenças médias, no início e no final da gestação, nos diâmetros de panturrilha direita, panturrilha esquerda, tornozelo direito e tornozelo esquerdo foram de, respectivamente, 0,30 cm, 0,30 cm, 0,15 cm e 0,15 cm no grupo intervenção e 1,95 cm, 1,95 cm, 1,73 cm e 1,87 cm no grupo controle. A maioria das gestantes não teve dificuldade para utilizar as meias de compressão, e todas relataram que sentiram diferença nos sintomas das pernas e que usariam as meias novamente. Conclusões As meias de compressão foram eficazes na prevenção de edema em membros inferiores de gestantes, as quais apresentaram percepção positiva quanto à sua utilização.

Abstract Background Pregnancy is characterized by physiological changes that can contribute to development of varicose veins, venous insufficiency, and leg edema. Objectives To evaluate the effect of compression stocking on lower limb edema in pregnant women and their perceptions of wearing them. Methods This was a randomized, controlled, prospective, parallel, blinded clinical trial conducted with 60 pregnant women randomly distributed into two groups: an intervention group (n = 30) wearing compression stockings and a control group (n = 30). Standardized ankle and calf measurements were taken of all 120 lower limbs using a tape measure. At the end of the study, a questionnaire was administered to identify perceived difficulties and advantages related to wearing compression stockings. Results Pregnant women in the intervention group had a significantly smaller increase (p < 0.05) in calf and ankle diameters compared to those in the control group. The mean differences from the beginning to the end of gestation in the diameters of the right calf, left calf, right ankle, and left ankle respectively were 0.30 cm, 0.30 cm, 0.15, cm and 0.15 cm in the intervention group and 1.95 cm, 1.95 cm, 1.73 cm, and 1.87 cm in the control group. Most of the pregnant women had no difficulty wearing the compression stockings and all reported that they felt a difference in leg symptoms and would wear stockings again. Conclusions Compression stockings were effective for preventing lower limb edema in pregnant women, who had a positive perception of wearing them.

Manejo anestésico de pacientes con trombocitemia esencial / Anesthetic management of a patient with essential trombocythemia

La trombocitemia esencial forma parte del grupo de neoplasias mieloproliferativas. Se caracteriza por síntomas microvasculares y vasomotores, recuento plaquetario superior a 450 x 109/l, proliferación megacariocítica con morfología grande y madura, ausencia de proliferación eritroide y granulocítica, demostración de JAK2V617F u otro marcador clonal y ausencia de evidencia de trombocitosis reactiva. Se reporta el manejo anestésico en una paciente donde las principales consideraciones están relacionadas con la prevención de eventos hemorrágicos y trombóticos. La suspensión de la aspirina, el mantenimiento del tratamiento con hidroxiurea, la preparación con ácido tranexámico, el uso pre y posoperatorio de fraxiparina, hidratación adecuada, uso de medias elásticas en miembros inferiores, deambulación precoz, buena hemostasia quirúrgica y disponibilidad de concentrados de plaquetas son los elementos fundamentales en la conducción anestésica de esta paciente(AU)

Essential thrombocythemia is part of the group of myeloproliferative neoplasms. It is characterized by microvascular and vasomotor symptoms, platelet count over 450x109/L, megakaryocytic proliferation with large and mature morphology, absence of erythroid and granulocytic proliferation, demonstration of JAK2V617F or other clonal marker, and absence of evidence of reactive thrombocytosis. Anesthetic management is reported in a patient, whose case's main considerations are related to the prevention of hemorrhagic and thrombotic events. Aspirin suspension, maintenance of hydroxyurea treatment, preparation with tranexamic acid, pre- and post-operative use of fraxiparin, adequate hydration, use of elastic stockings in lower limbs, early ambulation, good surgical hemostasis, as well as availability of platelet concentrates are the fundamental elements in the anesthetic management of this patient(AU)

Trombosis venosa profunda y trombofilia congénita / Deep-vein thrombosis and congenital thrombophilia

Introducción: La trombofilia es un desorden de la hemostasia congénito o adquirido que predispone al desarrollo de trombosis. Las trombofilias congénitas más frecuentes son las deficiencias de antitrombina III, proteína C y proteína S, el factor V Leiden, la mutación del gen de la protrombina (G20210A) y las mutaciones de la enzima metilentetrahidrofolato reductasa (MTHFR). Objetivo: Describir el manejo anestésico en un paciente portador de trombofilia congénita. Presentación del caso: Se reporta un paciente de 19 años de edad con antecedentes de historia familiar y personal de trombosis venosa profunda, tratamiento con doble antiagregación plaquetaria y asociación de tres mutaciones para trombofilia congénita, G20210A, A1298C MTHFR y C677T MTHFR que recibe anestesia espinal para una herniorrafia inguinal. Se mantiene tratamiento con aspirina, se suspende clopidogrel 7 días antes de la cirugía y durante ese tiempo se administra fraxiparina 0.6 Uds. subcutánea diarias hasta 12 h antes de la cirugía, se utiliza medias elásticas, deambulación precoz y reinicio de clopidogrel 24 h después de la cirugía, con evolución satisfactoria. Conclusiones: La tromboprofilaxis en pacientes portadores de trombofilia congénita es mandatoria, por eso resulta determinante la utilización de heparina de bajo peso molecular junto al resto de las medidas de prevención de la trombosis venosa profunda(AU)

Introduction: Thrombophilia is a congenital or acquired hemostasis disorder that predisposes to thrombosis development. The commonest congenital thrombophilias are deficiencies of antithrombin III, protein C and protein S, factor V Leiden, prothrombin gene mutation (G20210A), and methylenetetrahydrofolate reductase (MTHFR) mutations. Objective: To describe the anesthetic management in a patient with congenital thrombophilia. Case presentation: The case is reported of a 19-year-old patient with a family and personal history of deep-vein thrombosis, treatment with double antiplatelet therapy and association of three mutations for congenital thrombophilia (G20210A, A1298C MTHFR and C677T MTHFR), who receives spinal anesthesia for an inguinal herniorrhaphy. Aspirin treatment is maintained. Clopidogrel is suspended seven days before surgery. During this time, fraxiparin is administered subcutaneously in 0.6-mL units daily, up to twelve hours before surgery. Elastic stockings are used, early ambulation is allowed, and clopidogrel is restarted 24 hours after surgery, with satisfactory evolution. Conclusions: Thromboprophylaxis in patients with congenital thrombophilia is mandatory, a reason why the use of low-molecular-weight heparin, together with the rest of the prevention measures against deep-vein thrombosis, is decisive(AU)

Influence of the use of compression stockings on physiological, perceptual, and affective responses during running in recreational runners / Influência do uso de meias de compressão nas respostas fisiológicas, perceptuais e afetivas durante a corridas em corridores recreacionais

Este estudo objetivou comparar a influência do uso de polainas de compressão nas respostas fisiológicas, perceptuais e afetivas durante a corrida em corredores recreacionais. Dez corredores recreacionais (31,5 ± 9,7 anos) participaram deste estudo. Todos os sujeitos completaram três visitas ao laboratório: (a) familiarização e teste incremental até a exaustão (b) duas sessões de exercícios realizadas em dias diferentes. Cada sessão envolveu o mesmo protocolo de exercícios (20 minutos continuamente a uma intensidade de 80% da velocidade máxima da esteira a lcançada no teste incremental até a exaustão), com ou sem o uso de meias de compressão. A Felt Arousal Scale (FAS), Feeling Scale (FS), percepção subjetiva de esforço (PSE), o consumo de oxigênio (VO2) e a frequência cardíaca (FC) foram registradas durante cada sessão experimental. Os resultados não mostraram diferenças entre as condições fisiológicas (% VO2máx: 88,1 ± 8,3 vs 87,1 ± 11,32; % HR: 91,8 ± 2,8 vs 90,8 ± 3,2), e as respostas perceptuais (PSE: 6,4 ± 1,2 vs 6,2 ± 1,4) e afetivas (FS: 0,35 ± 2,4 vs 0,37 ± 2,3; FAS: 4,3 ± 0,7 vs 4,3 ± 1,1) durante cada sessão de exercício. Os resultados do presente estudo indicam que o uso de polainas de compressão não promove benefícios fisiológicos, perceptuais e afetivas durante a corrida em corredores recreacionais.(AU)

This study aimed to compare the influence of wearing compression stockings on physiological, perceptual, and affective respon ses during running in recreational runners. Ten recreational runners (31.5 ± 9.7 years) participated in this study. All subjects completed three visits to the lab: (a) familiarization and incremental test until exhaustion (b) two exercise sessions conducted on different days. Each session involved the same exercise protocol (20 min continuously at an intensity of 80% of the maximum treadmill speed achieved in the incremental test until exhaustion), with or without the use of compression stockings. The Felt Arousal Scale (FAS), Feeling Scale (FS), Rating of Perceived Exertion (RPE), oxygen consumption (VO2), and heart rate (HR) were recorded during each experimental session. Results showed no differ ences between the conditions of physiological (% VO2máx: 88.1 ± 8.3 vs 87.1 ± 11.32; % HR: 91.8 ± 2.8 vs 90.8 ± 3.2), perceptual (RPE: 6.4 ± 1.2 vs 6.2 ± 1.4) and affective (FS: 0.35 ± 2.4 vs 0.37 ± 2.3; FAS: 4.3 ± 0.7 vs 4.3 ± 1.1) responses during each exercise sessio n. The results of the present study suggest that wearing of compression stockings does not promote physiological, perceptual, and affective benefits during running of recreational runners.(AU)

Meias elásticas de compressão graduada como medida profilática de tromboembolismo venoso e edema de membros inferiores desencadeados por viagens aéreas: uma revisão sistemática de ensaios clínicos / Graduated compression stockings as a prophylactic measure in venous thromboembolism and edema of lower limbs triggered by air travel: a systematic review of clinical trials

Resumo Com o aumento da duração e frequência das viagens aéreas, observou-se um aumento da prevalência de tromboembolismo venoso nos passageiros. Este estudo avaliou a eficácia do uso de meias elásticas de compressão graduada para a prevenção de tromboembolismo venoso desencadeado por viagens aéreas com duração maior que 3 horas de voo. Trata-se de uma revisão sistemática de ensaios clínicos. A qualidade metodológica dos estudos e o nível de evidência científica foram avaliados pelo Consolidated Standards of Reporting Trials e Grading of Recommendations Assessment, Development and Evaluation. Foram identificados 34 artigos, entretanto apenas oito atenderam aos critérios de elegibilidade. Os desfechos incidência de tromboembolismo venoso e edema foram avaliados em 2.022 e 1.311 passageiros, respectivamente. Os estudos demonstraram evidências de alta qualidade para a prevenção de edema e de moderada qualidade para a redução da incidência de tromboembolismo venoso com o uso de meias elásticas de compressão graduada durante viagens aéreas.

Abstract The increase in duration and frequency of flights has led to an increase in the prevalence of venous thromboembolism among airline passengers. This study assesses the efficacy of graduated compression stockings for prevention of venous thromboembolism triggered by flights lasting more than 3 hours. The design is a systematic review of clinical trials. The methodological quality of studies and the level of scientific evidence were evaluated using the Consolidated Standards of Reporting Trials and Grading of Recommendations Assessment, Development and Evaluation standards. A total of 34 articles were identified, but only eight met the eligibility criteria. The outcomes incidence of venous thromboembolism and edema were assessed in 2,022 and 1,311 passengers, respectively. The studies presented high quality evidence demonstrating prevention of edema and moderate quality evidence of reduced incidence of venous thromboembolism associated with wearing graduated compression stockings during flights.

Insuficiência venosa crônica e uso de meia elástica de compressão graduada: uma análise sobre a adesão ao tratamento em pacientes do SUS / Chronic venous insufficiency and graduated compression stockings: analysis of public health system patients' adherence to treatment

Resumo Contexto A insuficiência venosa crônica é uma doença de alta prevalência mundial, podendo chegar a até 80% da população. Sua incidência aumenta com a idade e é mais frequente no sexo feminino. Das opções terapêuticas, destaca-se a terapia compressiva, sendo a principal o uso de meia elástica de compressão graduada, considerado o tratamento básico para a insuficiência venosa crônica independentemente da classificação clínica do paciente. Na prática clínica, o resultado da terapia é prejudicado pela não adesão ao uso da meia. Objetivos Avaliar a taxa de adesão ao uso da meia elástica de compressão graduada, assim como compreender a problemática da não aderência ao tratamento. Métodos Estudo observacional transversal, realizado entre junho de 2017 até janeiro de 2019, mediante aplicação de questionário aos pacientes em ambulatório de cirurgia vascular do Sistema Único de Saúde (SUS), em um hospital-escola, em Curitiba, no estado do Paraná (PR). Os dados foram analisados com o programa computacional IBM SPSS Statistics v.20.0. Resultados Foram analisados 240 pacientes. A média de idade foi de 57,5±12,9 (22-86); 84,2% eram do sexo feminino. Do total de pacientes analisados, 106 (44,2%) não aderiram ao uso das meias. As justificativas para o não uso foram: questão financeira, dor, desconhecimento da necessidade, calor e outras. Conclusões A taxa de adesão encontrada no presente estudo foi de 55,8%, e o principal motivo para o não uso foi a questão financeira.

Abstract Background Chronic venous insufficiency (CVI) is a pathology of great importance due to its high worldwide prevalence, affecting up to 80% of the population. Its incidence increases with age and is more frequent in females. One of the most important treatment options is compression therapy and the main method employed is wearing graduated compression stockings, which is considered the basic treatment for CVI regardless of the patient's clinical classification. In clinical practice, treatment outcomes are impaired by patients not wearing the stockings properly. Objectives To analyze the rate of adherence to wearing graduated compression stockings and to understand the problem of treatment non-adherence. Methods Cross-sectional observational study conducted from June 2017 to January 2019, based on administration of questionnaires to patients at a SUS vascular surgery clinic at a teaching hospital, in Curitiba, PR, Brazil. Data were analyzed using the IBM SPSS Statistics v.20.0 computer program. Results 240 patients were analyzed. Mean age was 57.5 ± 12.9 (22 - 86) and 84.2% of the sample were female. 106 of the 240 patients analyzed (44.2%) were non-adherent with wearing compression stockings. Reasons for not wearing the stockings were: financial; pain; ignorance of the need to wear them; heat; and others. Conclusions The adherence rate observed in the present study was 55.8% and the most prevalent reason for not wearing stockings was financial.

Avaliação da efetividade do uso de meias de compressão na prevenção do edema ocupacional em cabeleireiras / Evaluation of the effectiveness of wearing compression stockings for prevention of occupational edema in hairdressers

Resumo Contexto O edema ocupacional (EO) de membros inferiores (MMII) é um importante fator de queda na qualidade de vida, e a sua prevenção impõe a prescrição de medidas profiláticas, como o uso de meias de compressão (MCs). Objetivos Avaliar a efetividade das MCs na prevenção do EO e a sua repercussão na qualidade de vida de cabeleireiras. Métodos Este ensaio clínico realizou medidas de tornozelo e panturrilha de 38 cabeleireiras sem doença venosa no início e no final da jornada de trabalho em um momento sem e em outro usando MCs. Também responderam um questionário sobre sintomas e qualidade de vida em doença venosa. Resultados Os valores do ponto B foram de 21,1±2,2 cm no momento inicial sem meias, 22,1±2,3 cm no momento final sem meias (p = 0,0001 em relação ao inicial sem meias), e 21,2±2,1 cm no momento final com meias (p = 0,0001 em relação ao final sem meias). Não foi significante a diferença entre os valores médios do ponto B inicial sem meias e final com meias (p=0,324), ou seja, não houve formação de edema nos MMII ao final da jornada de trabalho em ortostatismo prolongado quando em uso de MCs. Pôde-se observar melhora da limitação sobre as atividades laborais (p = 0,0001), domésticas (p = 0,008) e de lazer ou sociais em pé (p = 0,0001). Conclusões As MCs são efetivas na prevenção do EO de MMII, e a atenuação de sintomas como dor e fadiga contribui diretamente para melhor qualidade de vida de cabeleireiras.

Abstract Background Occupational lower limb edema is an important factor in deterioration of quality of life. Prevention involves prescription of prophylactic measures, such as wearing compression stockings. Objectives To evaluate the effectiveness of compression stocking for prevention of occupational edema and its repercussions for the quality of life of hairdressers. Methods A clinical trial involving measurements of the ankles (point B) and calves (Point C) of 38 hairdressers without venous disease at the beginning and end of workdays spent wearing or not wearing compression stockings. Participants also answered a questionnaire about symptoms and quality of life in venous disease. Results Point B measurements were: 21.1 ± 2.2 cm in the morning without stockings; 22.1 ± 2.3 cm at the end of the day without stockings (p = 0.0001 compared to baseline without stockings); and 21.2 ± 2.1 cm at the end of the day wearing compression stockings (p = 0.0001 compared to the end of day not wearing compression stockings). The comparison between point B values for the start of the day without compression stockings and the end of the day with stockings (p = 0.324) was not significant, showing that there was no lower limb edema at the end of the working day when compression stockings were worn. Improvements were observed in ratings for limitations of work activities (p = 0.0001), domestic activities (p = 0.008) and leisure or social activities performed standing up(p = 0.0001). Conclusions Compression stockings are effective for preventing occupational lower limb edema and the attenuation of symptoms such as pain and fatigue directly contributes to better quality of life for hairdressers.

Deep Vein Thrombosis Due to Compression of Huge Hepatic Cyst Successfully Treated by Inferior Vena Cava Filter and Cyst Drainage / 대한소화기학회지

An 88-year-old woman complained of right quadrant abdominal pain and severe edema in both legs. She had a history of pulmonary embolism one month ago. Abdomen CT showed a huge hepatic cyst compressing the intrahepatic portion of the inferior vena cava (IVC). The venogram CT showed multifocal thrombosis in the iliocaval and both lower extremity veins. Percutaneous hepatic cyst drainage was carried out. Fluid analysis presented leukocytosis, which suggested an infected hepatic cyst. To prevent secondary pulmonary thromboembolism, an IVC filter was inserted before catheter drainage for the hepatic cyst. One week later, abdominal pain was relieved. Then, sclerotherapy for the remnant hepatic cyst was performed by ethanol. Follow-up CT showed an increased amount of thrombosis in the iliocaval and left calf vein, but the IVC filter prevented another thromboembolic event successfully. The patient started dabigatran, a new oral anticoagulant, and compression stockings were applied to both legs. After one month, no visible thrombosis in the pelvis or either extremity was detected in abdominal CT. This case suggests that a huge hepatic cyst, especially with infection, should be considered as a possible cause of deep vein thrombosis if no other risk factors for thromboembolism exist.

Compression stockings reduce the incidence of hypotension but not that of cerebral desaturation events in the beach-chair position: a randomized controlled trial / 대한마취과학회지

BACKGROUND: The beach-chair position (BCP) results in decreases in venous return, cardiac output, and cerebral perfusion pressure. In this randomized, prospective study, we investigated whether applying thigh-high compression stockings affected the maintenance of regional cerebral tissue oxygen saturation (rSO2) in the BCP. METHODS: Patients undergoing orthopedic surgery in the BCP under general anesthesia were included and assigned randomly to the control or the compression stocking group. Appropriately sized thigh-high compression stockings were applied to the patients in the stockings group. All patients were tilted, up to 45°, throughout the operation. Non-invasive blood pressure, invasive arterial blood pressure zeroed at the external auditory meatus, and rSO2 were recorded. RESULTS: Data were analyzed from 19 patients per group. In the BCP, the values of rSO2 and blood pressure decreased significantly compared with those at baseline, with no significant difference between the groups. The incidences of cerebral desaturation events (CDEs) were similar between the groups; however, that of hypotension was significantly lower in the compression stocking group. During 36 CDEs, the levels of rSO2 and blood pressure decreased significantly compared with those at baseline in both groups. No significant correlation was found between rSO2 and blood pressure. CONCLUSIONS: Thigh-high compression stockings reduced the incidence of hypotension but not that of CDEs. Our results suggest that other factors, beyond hypotension itself, contribute to CDEs and in other words, efforts just to reduce the incidence of hypotension may not mainly contribute to a reduction of CDEs occurrence in the BCP under general anesthesia.

Prevention, diagnosis and treatment of perioperative complications of bariatric and metabolic surgery / 中华胃肠外科杂志

Surgical operation in treating obesity and type 2 diabetes is popularizing rapidly in China. Correct prevention and recognition of perioperation-related operative complications is the premise of ensuring surgical safety. Familiar complications of the operation include deep venous thrombosis, pulmonary artery embolism, anastomotic bleeding, anastomotic fistula and marginal ulcer. The prevention of deep venous thrombosis is better than treatment. The concrete measures contain physical prophylaxis (graduated compression stocking and intermittent pneumatic compression leg sleeves) and drug prophylaxis (unfractionated heparin and low molecular heparin), and the treatment is mainly thrombolysis or operative thrombectomy. The treatment of pulmonary artery embolism includes remittance of pulmonary arterial hypertension, anticoagulation, thrombolysis, operative thrombectomy, interventional therapy and extracorporeal membrane oxygenation (ECMO). Hemorrhage is a rarely occurred but relatively serious complication after bariatric surgery. The primary cause of anastomotic bleeding after laparoscopic gastric bypass is incomplete hemostasis or weak laparoscopic repair. The common bleeding site in laparoscopic sleeve gastrectomy is gastric stump and close to partes pylorica, and the bleeding may be induced by malformation and weak repair technique. Patients with hemodynamic instability caused by active bleeding or excessive bleeding should timely received surgical treatment. Anastomotic fistula in gastric bypass can be divided into gastrointestinal anastomotic fistula and jejunum-jejunum anastomotic fistula. The treatment of postoperative anastomotic fistula should vary with each individual, and conservative treatment or operative treatment should be adopted. Anastomotic stenosis is mainly related to the operative techniques. Stenosis after sleeve gastrectomy often occurs in gastric angle, and the treatment methods include balloon dilatation and stent implantation, and surgical treatment should be performed when necessary. Marginal ulcer after gastric bypass is a kind of peptic ulcer occurring close to small intestine mucosa in the junction point of stomach and jejunum. Ulcer will also occur in the vestige stomach after laparoscopic sleeve gastrectomy, and the occurrence site locates mostly in the gastric antrum incisal margin. Preoperative anti-HP (helicobacter pylorus) therapy and postoperative continuous administration of proton pump inhibitor (PPI) for six months is the main means to prevent and treat marginal ulcer. For patients on whom conservative treatment is invalid, endoscopic repair or surgical repair should be considered. Different surgical procedures will generate different related operative complications. Fully understanding and effectively dealing with the complications of various surgical procedures through multidisciplinary cooperation is a guarantee for successful operation.

Síndrome de Klippel Trenaunay / Klippel-Trenaunay Syndrome

El Síndrome de Klippel Trenaunay es una malformación vascular congénita caracterizada por una triada de manifestaciones clínicas que comprende una malformación vascular venular, linfática y venosa, junto con hipertrofia esquelética y aumento de tejidos blandos de uno o más miembros. De etiología desconocida, patogénicamente se cree que se produce una alteración en el desarrollo del mesodermo en el feto, que afecta a las líneas angioblástica, linfoblástica y osteoblástica. Se presenta el caso de un paciente femenino de 5 años de edad quien presenta una malformación vascular, diagnosticada inicialmente como hemangioma vascular y posteriormente se asoció a Síndrome de Klippel Trenaunay. El objetivo de la presentación de este caso es generar conocimiento sobre las características clínicas del síndrome de Klippel Trenaunay para un diagnóstico y tratamiento oportuno(AU)

Klippel - Trenaunay -Weber congenital vascular malformation characterized by a triad of clinical manifestations comprising a venular, venous and lymphatic vascular malformation, with hypertrophy increased skeletal and soft tissue of one or more members. Of unknown etiology, it is believed to pathogenically an alteration occurs in mesoderm development in the fetus, which affects angioblastic , and osteoblastic lymphoblastoid lines. Is presentedthe case of a 5 year old that has a vascular malformation, initially diagnosed as vascular hemangioma and later was associated with Klippel- Trenaunay -Weber.Objective: To generate knowledge about the clinical features of KlippelTrenaunay Syndrome for diagnosis and treatment(AU)

Thromboembolism in pregnancy

Pregnancy-related venous thromboembolism (VTE) is one of the leading causes of maternal morbidity and mortality, developed in the antenatal and postpartum periods of pregnancy. The incidence of VTE during normal pregnancy is four- to six-fold higher than in the general reproductive aged female population. Physiologic changes such as hypercoagulable state, decreased venous capacitance, and reduced venous blood flow due to mechanical obstruction from gravid uterus compromise this condition. The prominent risk factors for VTE are thrombophilia, history of circulatory disease and previous VTE, preeclampsia and related disorders, and Cesarean section. In case of suspicion of VTE, prompt diagnosis and management are needed with the caution of potential adverse effects on the fetus. Low molecular weight heparin treatment is preferred due to better safety, more consistent bioavailability, ease of administration, lower risk of drug-related osteoporosis and thrombocytopenia and easier monitoring. For pregnant women with acute VTE, adjusted-dose subcutaneous low molecular weight heparin should be administrated antenatally and continued for at least 6 weeks postpartum. For prevention of VTE, mechanical prophylaxis such as physiotherapy, exercise, compression stockings, and intermittent pneumatic compression devices could be used. Thromboprophylaxis should also be considered for pregnant subjects with certain risks such as carriers of molecular thrombophilia or previously experienced VTE.

Prophylaxis for Venous Thromboembolism Following Total Knee Arthroplasty: A Survey of Korean Knee Surgeons

PURPOSE: The purpose of this study is to provide information on the actual status and prevailing trend of prophylaxis for venous thromboembolism (VTE) following total knee arthroplasty (TKA) in South Korea. MATERIALS AND METHODS: The Korean Knee Society (KKS) developed a questionnaire with 6 clinical questions on VTE. The questionnaire was distributed to all members of KKS by both postal and online mail. Participants were asked to supply details on their specialty and to select methods of prophylaxis they employ. Of the total members of KKS, 27.9% participated in the survey. RESULTS: The percentage of surgeons who routinely performed prophylaxis for VTE was 60.4%; 19.4% performed prophylaxis depending on the patient's health condition; and the remaining 20.2% never implemented prophylaxis after surgery. The common prophylactic methods among the responders were compression stocking (72.9%), pneumatic leg compression (63.3%), perioral direct factor Xa inhibitor (46.9%), and low-molecular-weight heparin (39.5%). For the respondents who did not perform prophylaxis, the main reason (51.5%) was the low risk of postoperative VTE considering the low incidences in Asians. CONCLUSIONS: The present study involving members of the KKS will help to comprehend the actual status of VTE prevention in South Korea. The results of this study may be useful to design VTE guidelines appropriate for Koreans in the future.

Avaliação do sistema de compressão de dois componentes no tratamento de úlcera varicosa / Evaluation of the two-component compression system for treatment of varicose ulcer / Evaluación del sistema de compresión de dos componentes para el tratamiento de úlcera varicosa

Os profissionais responsáveis pelo tratamento de pacientes com úlcera varicosa devem ser competentes na escolha e aplicação de terapias de compressão em consonância com as necessidades individuais dos pacientes. Para isso, faz-se necessário conhecer a performance dos produtos. OBJETIVO: avaliar o desempenho do sistema de compressão de duas bandagens no tratamento de úlcera varicosa. MÉTODO: estudo de caso descritivo de avaliação de produto com seguimento por 12 semanas de pacientes com idade superior a 20 anos, diagnóstico médico de úlcera varicosa, índice de pressão tornozelo/braço (ITB) > 0,8 e medidas da circunferência do tornozelo entre 18 e 25 cm ou 25 e 32 cm. As variáveis de desempenho foram a porcentagem da alteração da área; edema da perna; deslizamento da bandagem; eventos adversos. RESULTADOS: os participantes eram obesos, idade superior a 36 anos, ITB =1, edema na perna, relação circunferência panturrilha/tornozelo de 1,5, variação reduzida do movimento do tornozelo, úlceras com área de 1,0 a 5,4 cm². CONCLUSÃO: as variáveis utilizadas são adequadas para avaliação do desempenho de sistemas de compressão no tocante à porcentagem da alteração da área; edema da perna; deslizamento da bandagem; evento adverso (necrose na pele) e o sistema de dois componentes avaliado pode representar uma terapia adequada para tratamento de úlcera varicosa na prática clínica, no Brasil.

The professionals responsible for treating patients with varicose ulcer should be competent in the selection and application of compression therapy along with the patient's individual needs. For that, it is necessary to know the performance of the products. OBJECTIVE: To evaluate the performance of two compression systems bandages in the treatment of varicose ulcer. METHODS: descriptive case study of product evaluation with follow-up by 12 weeks of patients older than 20 years, medical diagnosis of varicose ulcers, ankle-brachial index (ABI) > 0.8 and measures of ankle circumference between 18 and 25 cm or 25 and 32 cm. The performance variables were the percentage of change in the area; leg edema; bandage slip; adverse events. RESULTS: The participants were obese, older than 36 years, ABI = 1, leg edema, calf/ankle circumference ratio of 1.5, reduced range of ankle motion, ulcers with an area from 1.0 to 5.4 cm². CONCLUSION: the variables used are suitable for performance assessment of compression systems with regard to the percentage of change in the area; leg edema; bandage slip; adverse event (necrosis of the skin) and the analyzed two-component system may be an appropriate therapy for the treatment of varicose ulcer in clinical practice in Brazil.

Los profesionales encargados del tratamiento de pacientes con úlcera varicosa deben ser competentes en la selección y aplicación de la terapia de compresión de acuerdo con las necesidades individuales de los pacientes. Para tal, es necesario conocer la performance de los productos. El objetivo del presente estudio ha sido evaluar el desempeho del sistema de compresión de dos vendajes en el tratamiento de úlcera varicosa. Se trata de un estudio de caso descriptivo de evaluación del producto con un seguimiento de 12 semanas de pacientes mayores de 20 ahos, con diagnóstico médico de úlceras varicosas, índice de presión tobillo/brazo (ITB) > 0,8 y medidas de la circunferencia del tobillo entre 18 y 25 cm o 25 y 32 cm. Las variables de desempeho fueron el porcentaje de alteración en la zona; edema en la pierna; deslizamiento del vendaje; eventos adversos. Los participantes eran obesos, mayores de 36 ahos, ITB = 1, edema en la pierna, relación de la circunferencia de pantorrilla/tobillo de 1.5, reducción de la amplitud de movimiento del tobillo, úlceras con un área de 1,0 a 5,4 cm2. Las variables utilizadas son apropiadas para la evaluación del rendimiento de sistemas de compresión con respecto al porcentaje de alteración en el área; edema en la pierna; deslizamiento del vendaje; evento adverso (necrosis de la piel) y el sistema de dos componentes evaluado puede ser una terapia adecuada para el tratamiento de úlcera varicosa en la práctica clínica en Brasil.

Quality of life in chronic venous patients who do or do not wear compressive stockings / Qualidade de vida em doentes venosos crônicos usuários e não usuários de meias elásticas

Wearing elastic compression stockings is of considerable significance for patients with chronic venous disease (CVD), since their physiological effect is to improve venous hemodynamic parameters, making them a good treatment option that can impact on patients' quality of life. OBJECTIVE: To assess quality of life in patients with chronic venous disease who do or do not wear elastic stockings. METHODS: This was a cross-sectional observational study assessing a sample of 50 CVD patients of both sexes, divided into two groups, one who wear elastic stockings and another who do not. Primary variables were the domains of the SF-36 (Medical Outcomes Study Short-form 36) and AVVQ (Aberdeen Varicose Veins Questionnaire) and secondary variables were: age; sex; physical activity; educational level; profession; wearing elastic stockings (frequency, pressure and type); elevation of lower limbs; itching and CEAP classification. The SF-36 and AVVQ quality of life questionnaires were administered to patients. Statistical significance was set at p<0.05. RESULTS: Wearing elastic stockings proved beneficial for the quality of life of people with chronic venous disease. For the AVVQ disease-specific questionnaire the greatest improvements were in overall score (p=0.0028) and the extent of varicosity domain (p=0.000). The SF-36 domains role emotional (p=0.017) and functional capacity (p=0.000) both improved. CONCLUSIONS: Wearing elastic stockings is an effective treatment for CVD that improves disease-specific quality of life and also leads to improvements in general quality of life...

O uso de Meias Elásticas Compressivas em pacientes com doença venosa crônica (DVC) é de grande significância, na medida em que reflete, na sua atuação fisiológica, melhora nos padrões hemodinâmicos venosos, configurando-se como boa opção terapêutica e podendo interferir na qualidade de vida do indivíduo. OBJETIVO: Avaliar a qualidade de vida de indivíduos com doença venosa crônica usuários e não usuários de meias elásticas. MÉTODOS: Trata-se de um estudo observacional de corte transversal, no qual foram avaliados 50 pacientes de ambos os sexos, com DVC, compondo dois grupos: um de usuários e o outro, de não usuários de meias elásticas. Teve, como variáveis primárias, os domínios dos questionários SF-36 (Medical Outcomes Study Short-form 36) e AVVQ (Aberdeen Varicose Veins Questionnaire); constituíram as variáveis secundárias: idade; sexo; atividade física; escolaridade; profissão; uso de meias elásticas (frequência de uso, pressão e tipo); elevação de membros inferiores; presença de prurido, e CEAP. Os pacientes responderam aos questionários de qualidade de vida SF-36 e AVVQ. A significância estatística considerada foi p<0,05. RESULTADOS: A utilização da meia elástica mostrou benefício na qualidade de vida dos indivíduos portadores de doença venosa crônica. O aspecto mais favorecido no questionário específico AVVQ relacionou-se à sua pontuação total (p=0,0028) e ao domínio Extensão da varicosidade (p=0,000). Já quanto ao SF-36, podem-se apontar o aspecto emocional (p=0,017) e a capacidade funcional (p=0,000). CONCLUSÃO: O uso de meias elásticas apresenta-se como uma terapêutica eficaz na DVC, melhorando a qualidade de vida específica e havendo, também, ganho na qualidade de vida geral...

Prevention Effects of Graduated Compression Stockings and Intermittent Pneumatic Compression on Deep Vein Thrombosis in SICU Patients: Pilot Study / 기본간호학회지

PURPOSE: The purpose of this pilot study was to investigate the effects of mechanical interventions for deep vein thrombosis (DVT) prophylaxis in surgical intensive care unit (SICU) patients. METHODS: The participants were assigned to the intermittent pneumatic compression (IPC) and graduated compression stocking (GCS) intervention. Patients who met the criteria were selected for comparison from our previous study. Data for 140 patients were included in the final analysis. RESULTS: The mean age was 57.5 (+/-15.7) and 61.4% were men. About forty-seven percent of the participants were 61 years or over. In the second duplex scan, 3, 2 and 1 critically ill patients developed deep vein thrombosis in the control, GCS, and IPC groups, respectively. Incidences of DVT were 6.0%, 5.0%, and 2.0% for the control, GCS, and IPC groups, respectively. This difference was not significant. Relative risks of no intervention were 3.0 and 1.2 compared with IPC and GCS application. There were no significantly different variables among the three groups before the intervention except for diagnosis on admission. CONCLUSION: Although it may difficult to conclude that mechanical prophylaxis effectively prevents DVT among SICU patients because there was no statistical significance in this study, but incidence rates among the three groups differed greatly. The findings reveal that further study should be conducted with larger samples and randomized controlled trial for SICU patients.

Incidence of Venous Thromboembolic Complications in Instrumental Spinal Surgeries with Preoperative Chemoprophylaxis

OBJECTIVE: Venous thromboembolism (VTE) after spinal surgery affects a patients' postoperative recovery and also carries a mortality risk. Some studies recommended chemical prophylaxis for high-risk patients and for those after complex spinal surgeries. However, chemoprophylaxis for VTE in spinal surgery is underemployed and there is no agreement on the use of VTE prophylaxis in spinal surgery. The aim of this study was to document the incidence of VTE after an elective instrumental spinal surgery, among those receiving preoperative chemoprophylaxis as compared with patients who did not receive it. METHODS: This study was carried out on eighty-nine patients allocated randomly to receive either low molecular weight heparin (LMWH) or no prophylaxis before elective instrumental spinal surgery. All patients received postoperative compression stockings. A compression Doppler ultrasonography was performed for all patients to detect postoperative deep vein thrombosis. In addition, further imaging studies were performed for patients suspected of VTE. RESULTS: Three (3.3%) patients were diagnosed with VTE. One of them had received preoperative chemoprophylaxis. There were no significant difference in incidence of VTE between the two groups (p>0.95; 95% confidence interval, 0.06-8.7). Laterality of gender and postsurgical recumbence duration were all independent predictors of VTE (p=0.01 and p<0.001, respectively). CONCLUSION: The difference in the incidence of thromboembolic complications between the two groups was not significant. Moreover, we found that preoperative prophylactic LMWH injection has no major bleeding complications altering postoperative course; still, the issue concerning the initiation time of chemoprophylaxis in spinal surgery remains unclear.

Clinical Performance of the 1st American Academy of Orthopaedic Surgeons Clinical Guideline on Prevention of Symptomatic Pulmonary Embolism after Total Knee Arthroplasty in Korean Patients

We sought to document the clinical performance of the 1st American Academy of Orthopaedic Surgeons (AAOS) guideline on the prevention of symptomatic pulmonary embolism (PE) after total knee arthroplasty (TKA) in Korean patients, in terms of the proportions of the each risk-stratified group, efficacy and safety. Consecutive 328 patients underwent TKA were preoperatively assessed for the risks of PE and bleeding and categorized into 4 groups: 1) standard risk, 2) high risk for PE, 3) high risk for bleeding, and 4) high risks both for PE and bleeding. One of three options was administered according to the groups (aspirin in group 1 or 4; enoxaparin and following aspirin in group 2; antithrombotic stocking in group 3). Incidences of symptomatic deep vein thrombosis (DVT) and PE, and major or minor bleeding complications were evaluated. Majority of the patients (86%) were assessed to be with standard risks both for PE and bleeding. No patient experienced symptomatic DVT or PE and major bleeding. Eleven percent of the patients discontinued chemoprophylaxis because of bleeding-related wound complication. In conclusion, the 1st AAOS guideline functions successfully in Korean patients undergoing TKA in terms of prevention of symptomatic DVT and PE while avoiding major bleeding complications.

Elaboração de vídeo educativo sobre uso da malha compressiva após queimadura / Educational video on use of compression garmet after burn

Introdução: As vestes compressivas são parte do tratamento ambulatorial das queimaduras profundas. Muitas vezes, os pacientes acabam por não utilizar a malha compressiva devido, principalmente, ao incômodo, à vergonha e ao desconhecimento sobre a importância do uso. Objetivo: Descrever o processo de construção de um vídeo educativo sobre a importância do uso da malha compressiva para indivíduos que sofreram queimaduras. Métodos: A construção do material educativo ocorreu nas seguintes etapas: revisão da literatura, análise dos dados coletados, elaboração e avaliação de roteiro e filmagem de três pacientes e dois pais e/ou responsáveis, no Ambulatório do Centro de Tratamento de Queimados do Hospital Universitário da Universidade Estadual de Londrina (CTQ/HU/UEL) e edição do vídeo. Resultados: Obteve-se um vídeo educativo que aborda a cicatrização hipertrófica, a colocação da malha compressiva, esclarecimentos de dúvidas e dicas de cuidados. Conclusão: O desenvolvimento de tecnologias educativas direcionadas ao tratamento do paciente vítima de queimadura constitui grande desafio, havendo a necessidade urgente em desenvolver novos materiais.

Introduction: The compressive garments are part of outpatient treatment of deep burns. Often patients end up not using the compression garment mainly due to discomfort, shame and ignorance of the importance of using. Objective: To describe the process of building an educational video on the importance of using the compression garment for individuals who have suffered burns. Methods: The construction of educational material occurred in the following steps: literature review, data analysis, drafting and review script and shooting of three patients and two parents and/or guardians in the Outpatient Burn Treatment Center University Hospital of the State University of Londrina (CTQ/HU/UEL) and editing the video. Results: An educational video that addresses the hypertrophic scarring, the placement of the compression garment, clarification of doubts and care tips was obtained. Conclusion: The development of educational technologies targeted to the treatment of burn victim patient is a great challenge and there is an urgent need to develop new materials.

Meias elásticas de compressão: estratégia para promoção da saúde de enfermeiros emergencistas / Compression hosiery: strategies for health promotion of emergency nurses / Medias elásticas de compresión: estrategia para promoción de la salud deenfermeros de emergencia

Buscou-se verificar se profissionais de enfermagem usam meias de compressão elásticas (MCE), visando à proteçãoe promoção da saúde; identificar o que leva esses profissionais a usarem ou não MCE; discutir os achados e suas implicações para a saúde desses trabalhadores. Estudo descritivo-exploratório, quantitativo, realizado em unidade de emergência do Rio deJaneiro - Brasil, entre abril de 2012 e outubro de 2013. Participaram 40 sujeitos, entre enfermeiros e técnicos de enfermagem. Os resultados indicaram que 20% usam MCE, 12,5% dos quais o fazem conforme o preconizado em literatura. Emergiu a categoria temática ‘Cuidam e esquecem de se cuidar - o desconhecimento dos benefícios do uso de MCE’. Os sujeitos justificam o não uso de MCE por considerarem o seu alto custo e o desconhecimento dos seus benefícios, apontado pela maioria dos profissionais. Concluiu-se que os elevados custos associados ao desconhecimento desses recursos determinam a não utilização das MCE.

Objectives were [1] to assess the use of compression hosiery by nurses for health protection and promotion; [2] toidentify whether or not and why or why not those professionals wear compression hosiery; and [3] to discuss the implications of the findings to the health of those professionals. This is a descriptive exploratory study on the basis of a quantitative method, developed in an emergency unit of Rio de Janeiro, RJ, Brazil, from April, 2012 to October, 2013. It included 40 subjects, including nurses and nursing staff and the results indicated that only 20% of the population in the study wear compression hosiery and only 12.5% of those follow literature for hosiery wear. High product cost accounted for not wearing compression hosiery. An analysis category emerged ‘Care and forget to take self-care - ignoring benefits of use of compression hosiery’. Subjects explained non-use on the basis of their high cost as well as for ignoring benefits, acknowledged by most professionals. Conclusions show that both high cost and ignorance of effects of compression hosiery wear determine non-use by those professionals.

Se buscó verificar se profesionales de enfermería usan medias elásticas de compresión (MCE), mirando a la protecejón y promoción de la salud; Identificar lo que lleva eses profesionales a usar o no MCE; Discutir los hallazgos y sus implicacionespara la salud de eses trabajadores. Estudio descriptivo-exploratorio, cuantitativo, hecho em unidad de emergência de Rio de Janeiro – Brasil, entre abril de 2012 y octubre de 2013. Participaron 40 sujetos, entre enfermeros y técnicos de enfermería. Los resultados indicaron que 20% usan MCE, 12,5 de los cuales lo hacen según es preconizado em literatura. Emergió la categoría temática. Cuidan y olvidan de cuidarse – el desconocimiento de los benefícios del uso de MCE. Los sujetos justifican no usar MCE por considerar su alto costo y por desconocer sus benefícios, todo eso apuntado por la mayoría de los professionales. Seconcluyó que el costo elevado asociado al desconocimiento de esos recursos determinan la no utilización de las MCE.